Managing CJD/vCJD risk in  Ophthalmology October 2009

(http://www.dh.gov.uk/ab/ACDP/TSEguidance/index.htm )

National RCOphth (UK) Guidelines for Intravitreal Injections Procedure 2009 (http://www.rcophth.ac.uk/docs/scientific/IVTRevisionfinal2009.pdf)

Guidelines for Ranibizumab: The clinician's guide to commencing, continuing, and discontinuing treatment 2008

(http://www.rcophth.ac.uk/docs/scientific/Ranibizumab_-_June_2008.pdf)

Medical therapies for diabetic eye diseases- how good are they ? 

Pearce IA and Harding SP

Chapter 18 of Evidenced-based Management of Diabetes. 2012 TFM Publishing

Scleral Perforations

Konstanidis L and Pearce IA

Chapter 5 of Complications of Vitreo-Retinal Surgery. 2013 Lippincott, Williams & Wilkins

Ophthalmology

Pearce IA

Barton and Power’s Clinical Negligence, 2015 Bloomsbury Press

Guidance for anti-VEGF intravitreal injections during the COVID-19 pandemic.

Korobelnik JF, Loewenstein A, Eldem B, Joussen AM, Koh A, Lambrou GN, Lanzetta P, Li X, Lövestam-Adrian M, Navarro R, Okada AA, Pearce I, Rodríguez FJ, Wong DT, Wu. 

Graefes Arch Clin Exp Ophthalmol. 2020 Apr 23. doi: 10.1007/s00417-020-04703-x. [Epub ahead of print] Review.

Fundamental principles of an effective diabetic retinopathy screening program.

Lanzetta P, Sarao V, Scanlon PH, Barratt J, Porta M, Bandello F, Loewenstein A; Vision Academy, Eldem B, Hunyor A, Joussen A, Koh A, Korobelnik JF, Lanzetta P, Loewenstein A, Lövestam-Adrian M, Navarro R, Okada AA, Pearce I, Rodríguez FJ, Staurenghi G, Wolf S, Wong DT.

Acta Diabetol. 2020 Mar 28. doi: 10.1007/s00592-020-01506-8. [Epub ahead of print]

Suspending treatment of neovascular age-related macular degeneration in cases of futility.

Wong DT, Lambrou GN, Loewenstein A, Pearce I, Okada AA.

Retina. 2019 Dec 24. [Epub ahead of print]

Effect of inverted internal limiting membrane flap on closure rate, postoperative visual acuity, and restoration of outer retinal layers in primary idiopathic macular hole surgery.

Baumann C, Kaye S, Iannetta D, Sultan Z, Dwivedi R, Pearce I.

Retina. 2019 Dec 10. [Epub ahead of print]

Translating evidence into practice: recommendations by a UK expert panel on the use of aflibercept in diabetic macular oedema.

Pearce I, Bailey C, Fletcher E, Ghanchi F, Rennie C, Santiago C, Napier J, Yang Y.

Eye (Lond). 2019 Oct 16. [Epub ahead of print]

Anatomical and functional outcomes following switching from aflibercept to ranibizumab in neovascular age-related macular degeneration in Europe: SAFARI study.

Gale RP, Pearce I, Eter N, Ghanchi F, Holz FG, Schmitz-Valckenberg S, Balaskas K, Burton BJL, Downes SM, Eleftheriadis H, George S, Gilmour D, Hamilton R, Lotery AJ, Patel N, Prakash P, Santiago C, Thomas S, Varma D, Walters G, Williams M, Wolf A, Zakri RH, Igwe F, Ayan F.

Br J Ophthalmol. 2019 Aug 5. [Epub ahead of print]

Patient-reported outcomes in the RELIGHT clinical trial of ranibizumab in diabetic macular oedema.

Chakravarthy U, Pearce I, Banerjee S, Burton BJL, Downey L, Gale R, Patel J, Patra S, Sivaprasad S, Stevenson M, Lupton S.

BMJ Open Ophthalmol. 2019 Apr 30;4(1)

Dexamethasone implant for non-infectious uveitis: is it cost-effective?

Squires H, Bermejo I, Poku EN, Cooper K, Stevens J, Hamilton J, Wong R, Denniston AK, Pearce I, Quhill FM.

Br J Ophthalmol. 2019 Nov;103(11):1639-1644.

Adalimumab for non-infectious uveitis: is it cost-effective?

Bermejo I, Squires H, Poku EN, Cooper K, Stevens JW, Hamilton J, Wong R, Pearce I, Quhill FM, Denniston AK.

Br J Ophthalmol. 2019 Nov;103(11):1633-1638

Association between diabetic eye disease and other complications of diabetes: implications for care. A systematic review.

Pearce IA, Simó R, Lövestam-Adrian M, Wong DT, Evans M.

Diabetes Obes Metab. 2019 Mar;21(3):467-478

The role of OCT-A in retinal disease management.

Rodríguez FJ, Staurenghi G, Gale R; Vision Academy Steering Committee.

Graefes Arch Clin Exp Ophthalmol. 2018 Nov;256(11):2019-2026

Clinical outcomes in Caucasian patients with polypoidal choroidal vasculopathy.

Agorogiannis, EI, Pearce IA, Yadav S, Parry DG, Beare NAV.

Eye (Lond). 2018 Nov;32(11):1731-1739

A noninterventional study to monitor patients with diabetic macular oedema starting treatment with ranibizumab (POLARIS).

Stefanickova J, Cunha-Vaz J, Ulbig M, Pearce I, Fernandez -Vega Sanz A, Theodossiadis P, Kodjikian L, Izmailov A, Muston D, Vassilev Z, Lamotte B, Tückmantel C, Friedl S, Altemark A, Schwarz HJ, Katz T; POLARIS study investigators.

Acta Ophthalmol. 2018 Dec;96(8):e942-e949

A systematic review and economic evaluation of adalimumab and dexamethasone for treating non-infectious intermediate uveitis, posterior uveitis or panuveitis in adults.

Squires H, Poku E, Bermejo I, Cooper K, Stevens J, Hamilton J, Wong R, Denniston A, Pearce I, Quhill F.

Health Technol Assess. 2017 Nov;21(68):1-170.

Sustained Benefits of Ranibizumab with or without Laser in Branch Retinal Vein Occlusion: 24-Month Results of the BRIGHTER Study.

Tadayoni R, Waldstein SM, Boscia F, Gerding H, Gekkieva M, Barnes E, Das Gupta A, Wenzel A, Pearce I; BRIGHTER Study Group.

Ophthalmology. 2017;124(12):1778-1787. 

Polypoidal choroidal vasculopathy: a common type of neovascular age-related macular degeneration in Caucasians.

Yadav S, Parry DG, Beare NAV, Pearce IA.

Br J Ophthalmol. 2017;101(10):1377-1380. 

Individualized Stabilization Criteria-Driven Ranibizumab Versus Laser in Branch Retinal Vein Occlusion: 6-Month Results Of BRIGHTER 

Tadayoni R, Waldstein SM, Boscia F, Gerding H, Pearce I, Priglinger S, Wenzel A, Barnes E Gekkieva M, Pilz S, Monés J, on behalf of the BRIGHTER study group.

Ophthalmology 2016;123:1332-44

Individualized Ranibizumab Regimen Driven by Stabilization Criteria for Central Retinal Vein Occlusion: Twelve-Month Results of the CRYSTAL Study.

Larsen M, Waldstein SM, Boscia F, Gerding H, Monés J, Tadayoni R, Priglinger S, Wenzel A, Barnes E, Pilz S, Stubbings W, Pearce I; CRYSTAL Study Group.

Ophthalmology 2016;123:1101-11

Ranibizumab 0.5 mg for Diabetic Macular Edema with Bimonthly Monitoring after a Phase of Initial Treatment: 18-Month, Multicenter, Phase IIIB RELIGHT Study.

Pearce I, Banerjee S, Burton BJ, Chakravarthy U, Downey L, Gale RP, Gibson J, Pagliarini S, Patel J, Sivaprasad S, Andrews C, Brittain C, Warburton J; RELIGHT Study Group.

Ophthalmology. 2015 Sep;122(9):1811-9

Ranibizumab in retinal vein occlusion: treatment recommendations by an expert panel.

Gerding H, Monés J, Tadayoni R, Boscia F, Pearce I, Priglinger S.

Br J Ophthalmol. 2015 Mar;99(3):297-304

Efficacy and safety of widely used treatments for macular oedema secondary to retinal vein occlusion: a systematic review.

Glanville J, Patterson J, McCool R, Ferreira A, Gairy K, Pearce I.

BMC Ophthalmol. 2014 Jan 21;14:7. 

Epimacular brachytherapy for neovascular age-related macular degeneration (CABERNET): fluorescein angiography and optical coherence tomography.

Jackson TL, Dugel PU, Bebchuk JD, Smith KR, Petrarca R, Slakter JS, Jaffe GJ, Nau JA; CABERNET Study Group.

Ophthalmology. 2013 Aug;120(8):1597-603. 

Reeves GM, Kumar N, Beare NA, Pearce IA.

Acta Ophthalmol. 2013 Feb;91(1):48-51

Owen ME, Beare NA, Pearce IA, Mewar D.

Intravitreal tumor necrosis factor inhibitors in the treatment of refractory diabetic macular edema.

Retina. 2012 Nov-Dec;32(10):2179; author reply 2179-80.

Retrospective review of 50 eyes with long-term silicone oil tamponade for more than 12 months.

Morphis G, Irigoyen C, Eleuteri A, Stappler T, Pearce I, Heimann H.

Graefes Arch Clin Exp Ophthalmol. 2012 May;250(5):645-52.

Kumar A, Ziahosseini K, Saeed MU, Pearce IA, Beare NAV.

Retinal Cases & Brief Reports.2012; 6(2):153-155

Ternent L, Vale L, Boachie C, Burr JM, Lois N; Full-Thickness Macular Hole and Internal Limiting Membrane Peeling Study (FILMS) Group.

Br J Ophthalmol. 2012 Mar;96(3):438-43

Haller JA, Bandello F, Belfort R Jr, Blumenkranz MS, Gillies M, Heier J, Loewenstein A, Yoon YH, Jiao J, Li XY, Whitcup SM;, Li J. Ozurdex GENEVA Study Group

Ophthalmology. 2011 Dec;118(12):2453-60.

Heavy silicone oil versus standard silicone oil in as vitreous tamponade in inferior PVR (HSO Study): interim analysis.

Joussen AM, Rizzo S, Kirchhof B, Schrage N, Li X, Lente C, Hilgers RD; HSO -Study Group.

Acta Ophthalmol. 2011 Sep;89(6):e483-9.

Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR Study): predictive factors for functional outcome. Study report no. 6.

Heussen N, Feltgen N, Walter P, Hoerauf H, Hilgers RD, Heimann H; SPR Study Group.

Graefes Arch Clin Exp Ophthalmol. 2011 Aug;249(8):1129-36

Internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole: a pragmatic randomized controlled trial.

Lois N, Burr J, Norrie J, Vale L, Cook J, McDonald A, Boachie C, Ternent L, McPherson G; Full-thickness Macular Hole and Internal Limiting Membrane Peeling Study (FILMS) Group.

Invest Ophthalmol Vis Sci. 2011 Mar 1;52(3):1586-92.

Abatacept: a potential therapy in refractory cases of juvenile idiopathic arthritis associated

uveitis.

Kenawy N, Cleary G, Mewar D, Beare N, Chandna A, Pearce I.

Graefes Arch Clin Exp Ophthalmol. 2011 Feb;249(2):297-300.

Intravitreal bevacizumab for retinal vein occlusion and early growth of epiretinal

membrane: a possible secondary effect?

Marticorena J, Romano MR, Heimann H, Stappler T, Gibran K, Groenewald C, Pearce I, Wong D.

Br J Ophthalmol. 2011 Mar;95(3):391-5.

Incidence of neovascularization in the fellow eye of patients with unilateral retinal angiomatous proliferation.

Campa C, Harding SP, Pearce IA, Beare NA, Briggs MC, Heimann H.

Eye (Lond). 2010 Oct;24(10):1585-9

Dietary supplements in AMD – an Update.

Pearce IA.

RCOphth Focus Article Summer 2010

Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion.

Haller JA, Bandello F, Belfort R Jr, Blumenkranz MS, Gillies M, Heier J,

Loewenstein A, Yoon YH, Jacques ML, Jiao J, Li XY, Whitcup SM; OZURDEX

GENEVA Study Group.

Ophthalmology. 2010 Jun;117(6):1134-1146

Paraneoplastic exudative retinal detachment associated with adenocarcinoma of the lung. 

Burgess PI, Kenawy N, Pearce IA.

Eur J Ophthalmol. 2010 Feb 25.

Bevacizumab (Avastin) as a surgical adjunct in diabetic vitrectomy for fibrovascular disease.

Gandhi JS, Tan LT, Pearce I, Charles SJ.

Eye (Lond). 2009 Mar;23(3):742-3.

Ranibizumab: The clinician's guide to commencing, continuing, and discontinuing treatment.

Amoaku W; National Institute for Health and Clinical Excellence; Royal College of Ophthalmologists (RCOphth); Department of Health; Writing Committee

Eye (Lond). 2009 Nov;23(11):2140-2.

[Densiron-68 heavy silicone oil in cases of PVR. Anatomic and functional

outcomes].

Stappler T, Heimann H, Gibran SK, Groenewald C, Pearce IA, Wong D.

Ophthalmologe. 2009 Apr;106(4):320-6.

Observational prospective study of the effectiveness in routine clinical practice of verteporfin photodynamic therapy in patients with neovascular age-related macular degeneration.Murjaneh S, García-Fiñana M, Mahmood S, Lenfestey PM, Taylor SA, Pearce IA, Briggs MC, Heimann H, Harding SP.

Br J Ophthalmol. 2009 Apr;93(4):468-73.

Uveitis triggered by acute onset gastroenteritis.

Cazabon S, Quah SA, Pearce IA, Harding SP.

Int J Clin Pract. 2008 Dec;62(12):1957-8.

Cytomegalovirus retinitis in the absence of HIV or immunosuppression.

Sloan DJ, Taegtmeyer M, Pearce IA, Hart IJ, Miller AR, Beeching NJ.

Eur J Ophthalmol. 2008 Sep-Oct;18(5):813-5.

Clinical and cost-effectiveness of internal limiting membrane peeling for patients with idiopathic full thickness macular hole. Protocol for a randomised controlled trial: FILMS (Full-thickness Macular Hole and Internal Limiting Membrane Peeling Study).

Lois N, Burr J, Norrie J, Vale L, Cook J, McDonald A; Full-Thickness Macular

Hole and Internal Limiting Membrane Peeling Study (FILMS) Group.

Trials. 2008 Nov 3;9:61.

Heavy tamponade 2 Densiron 68 in routine clinical practice: anatomical and functional outcomes of a consecutive case series.

Stappler T, Heimann H, Wong D, Gibran SK, Groenewald C, Pearce IA.

Eye (Lond). 2008 Oct;22(10):1360-5.

Primary vitrectomy with Densiron-68 for rhegmatogenous retinal detachment.

Romano MR, Stappler T, Marticorena J, Groenewald C, Pearce I, Gibran SK, Wong D, Heimann H.

Graefes Arch Clin Exp Ophthalmol. 2008 Nov;246(11):1541-6.

Peel and peel again 

Gibran SK, Flemming B, Stappler T, Pearce I, Groenewald C, Heimann H, Hiscott P, Wong D.

Br J Ophthalmol. 2008 Mar;92(3):373-7.

The introduction of verteporfin photodynamic therapy in the UK: PDT users group (PDTUG) surveillance programme report 1.

Ghanchi FD, Fullarton J, Blake J, Harding SP; PDTUG(UK).

Eye (Lond). 2008 May;22(5):671-7.

Glycaemic control and control of risk factors in diabetes patients in an ophthalmology clinic: what lessons have we learned from the UKPDS and DCCT studies?

Higgins GT, Khan J, Pearce IA.

Acta Ophthalmol Scand. 2007 Nov;85(7):772-6.

Early vitrectomy for fundus-obscuring dense vitreous haemorrhage from presumptive retinal tears. 

Dhingra N, Pearce I, Wong D.

Graefes Arch Clin Exp Ophthalmol. 2007 Feb;245(2):301-4.

Kumar N, Sebastian R, Harding S, Pearce I.

Bevacizumab: a word of caution.

Can J Ophthalmol. 2007 Oct;42(5):760-1.

Successful retrieval of internal limiting membrane specimens.

Gibran SK, Prime W, Cazabon J, Stappler T, Heimann H, Pearce I, Groenewald C, Wong D, Hiscott P.

Eye (Lond). 2007 Feb;21(2):298-9.

Optimizing the use of tumornecrosis factor alpha inhibitors in refractory uveitis.

Sebastian RT, Harding SP, Bucknall RC, Pearce IA.

Arch Ophthalmol. 2006 Oct;124(10):1505

Mycophenolate mofetil as an immunosuppressive agent in refractory inflammatory eye disease.

Choudhary A, Harding SP, Bucknall RC, Pearce IA.

J Ocul Pharmacol Ther. 2006 Jun;22(3):168-75.

Can the sequential use of conventional silicone oil and heavy oil be a strategy for the management of proliferative vitreoretinopathy?

Wong D, Cazabon S, Ali H, Kumar I, Valldeperas X, Groenewald C, Pearce I.

Ann Acad Med Singapore. 2006 Mar;35(3):181-4.

Visual loss following removal of intraocular silicone oil.

Cazabon S, Groenewald C, Pearce IA, Wong D.

Br J Ophthalmol. 2005 Jul;89(7):799-802.

A pilot study on the use of a perfluorohexyloctane/silicone oil solution as a heavier than water internal tamponade agent.

Wong D, Van Meurs JC, Stappler T, Groenewald C, Pearce IA, McGalliard JN,

Manousakis E, Herbert EN.

Br J Ophthalmol. 2005 Jun;89(6):662-5.

Dietary supplements in AMD 

Pearce IA 

RCOphth Focus Article Summer 2004

Vitreous penetration of levofloxacin in the uninflamed phakic human eye.

Herbert EN, Pearce IA, McGalliard J, Wong D, Groenewald C.

Br J Ophthalmol. 2002 Apr;86(4):387-9.

Stabilisation of diabetic retinopathy following simultaneous pancreas and kidney transplant.

Pearce IA, Ilango B, Sells RA, Wong D.Br J Ophthalmol. 2000 Jul;84(7):736-40.

Vertical diplopia following local anaesthetic cataract surgery: predominantly a left eye problem?

Pearce IA, McCready PM, Watson MP, Taylor RH.Eye (Lond). 2000 Apr;14 ( Pt 2):180-4.

Valsalva retinopathy associated with blowing balloons.

Georgiou T, Pearce IA, Taylor RH.

Eye (Lond). 1999 Oct;13 ( Pt 5):686-7.

Three year visual outcome for treated stage 3 retinopathy of prematurity: cryotherapy versus laser.

Pearce IA, Pennie FC, Gannon LM, Weindling AM, Clark DI.

Br J Ophthalmol. 1998 Nov;82(11):1254-9.

Visual function and patient satisfaction after macular hole surgery.

Pearce IA, Branley M, Groenewald C, McGalliard J, Wong D.

Eye (Lond). 1998;12 ( Pt4):651-8.

Nasal epipapillary membrane causing visual field loss following macular hole surgery: does it throw fresh light on the retinotopic arrangement of the nerve fibre layer?

Groenewald CP, Wong D, Pearce I, Hiscott P, Grierson I.

Eye (Lond).1998;12 ( Pt 2):328-30.

Does cryotherapy before drainage increase the risk of intraocular haemorrhage and affect outcome? A prospective, randomised, controlled study using a needle drainage technique and sustained ocular compression.

Pearce IA, Wong D, McGalliard J, Groenewald C.

Br J Ophthalmol. 1997 Jul;81(7):563-7.

Pseudocystic ultrasound appearance of choroidal melanoma. 

Pearce IA, Smith PA, Damato BE.

Br J Ophthalmol. 1997 Jun;81(6):517.

Glutamate acting on NMDA ,receptors stimulates neurite outgrowth from cerebellar granule cells.

Pearce IA, Cambray-Deakin MA, Burgoyne RD. 

FEBS Lett. 1987 Oct 19;223(1):143-7.

N-methyl-D-aspartate raises cytosolic calcium concentration in rat cerebellar granule cells in culture.

Burgoyne RD, Pearce IA, Cambray-Deakin M.

Neurosci Lett. 1988 Aug 15;91(1):47-52.